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In vivo drug imaging device (coherent Raman microscopy system)

Successful measurement of the concentration distribution of low molecular weight compounds administered to mouse tissues: A new method for elucidating drug action mechanisms in living organisms.

● We have developed a method to measure the concentration distribution of low molecular weight compounds in moist tissues. ● A pathway has been opened for the localization measurement of drugs and low molecular weight bioactive substances in biological tissues. ● In the future, applications for elucidating the mechanisms of action of low molecular weight bioactive substances and developing new therapeutic drugs are expected. 【Features of the device】 1. Device adjustment frequency -------------------- Continuous, no adjustment needed 2. Measurement time after power on ----------- Immediate measurement possible 3. Time required for initial measurement adjustment after installation ------- Less than 2 hours 4. Direct measurement ---------------- Measurement without using fluorescent substances 5. Compact size, cost reduction ------------ Composed of only one femtosecond laser 【Samples and specimens that can utilize this technology】 1. Non-destructive, non-contact measurement 2. Identification of molecular structures 3. Measurement of depth distribution of samples 4. Samples containing moisture at room temperature in the atmosphere 5. Plants, insects, fish, etc. (Note: Some measurement objects may not be measurable)